InfusionJobsFor Employers
Home / Guides / PRN infusion nurse

PRN infusion nurse: how per diem infusion work works

A PRN (per diem) infusion nurse is an RN who works infusion shifts as needed instead of a set schedule. You fill in for vacations, busy days and new locations, and in return you choose when you work. PRN is common in infusion: 81 of the 259 infusion RN posts on this site (31%) are per diem.

PRN infusion nursing at a glance
  • Hours: not guaranteed. Most employers set a minimum, such as a number of shifts a month.
  • Benefits: usually none, or limited. That's the trade for flexibility.
  • Pay: hourly. Median $47/hr across 5 PRN posts that list a rate.
  • Who it suits: nurses with another job, parents, students, or experienced RNs who want to stay in infusion part-time.

How PRN infusion shifts work

Ambulatory infusion centers schedule patients in advance, so PRN shifts are usually posted days or weeks ahead rather than called in that morning. Chains with several locations often use PRN nurses to cover a region, so you may float between sites. Home infusion companies use PRN nurses for visits in a territory. Ask how far you may be asked to travel and whether mileage is paid.

PRN pay vs. staff pay

In current posts, PRN infusion RNs have a median of $47 an hour, against $48 for all infusion RN posts that list hourly pay. Some employers add a premium to make up for having no benefits. Others pay PRN and staff nurses the same base rate, so compare total compensation, not just the hourly number. More in our infusion nurse salary guide.

Who is hiring PRN infusion nurses

EmployerPRN infusion RN posts
LUX Infusion40
Druid City Infusion9
PURE Infusion8
IVX Health7
KabaFusion5

Counted from current posts on InfusionJobs, updated weekly.

Questions to ask before you take a PRN role

You'll still interview like any infusion RN, so prepare with our infusion nurse interview questions. If you're weighing PRN home infusion, read home infusion vs. infusion center nursing.

Find PRN infusion nurse jobs

See every opening on our PRN infusion nurse jobs page, or by state: California, Colorado, Wyoming, New York, Tennessee, Georgia, Arizona, Texas.

How we write our guides. Certification, pay and practice facts are checked against primary sources (INCC/INS, ONS, the U.S. Bureau of Labor Statistics), listed at the end of the guide where they apply. Pay and job counts come from the job posts on this site and update weekly. These guides describe careers and job duties. They aren't clinical advice: follow your orders, your employer's protocols and the product labeling. More about our data.

544 infusion jobs open right now

Including 277 infusion RN roles, pulled straight from employer careers pages every week.

Browse infusion jobs

More guides

Infusion nurse salary: what infusion RNs get paidInfusion nurse pay from current job posts at infusion centers, how it compares with the BLS median for all RNs and what moves pay up: PRN, setting, location.5 min readHome infusion vs infusion center nursing: which fits you?How home infusion nursing compares with working in an ambulatory infusion center: autonomy, driving, pay models, schedules, and who each suits.5 min readInfusion nurse interview questions (and how to answer them)15 questions infusion centers and home infusion companies ask RNs, on IV starts, infusion reactions, ports and PICCs, and patient teaching, with what to say.7 min read

All infusion nursing guides